Raw DNA Health Result: What Needs Clinical Confirmation?

A third-party interpretation of consumer raw DNA can produce false-positive findings. A flagged result needs appropriate clinical confirmation before it is used for healthcare decisions. That does not mean your particular finding is false.

This page concerns adults with an existing raw-data health claim. It does not interpret a variant or recommend a genetic test. Do not delay care for symptoms while clarifying it.

The testing company's report, a downloaded genotype file and a separate interpreter's report are different outputs. Keep their source and dates clear rather than treating every document as the original test's conclusion.

Consumer-initiated services can involve a clinician in different ways. Ask what your actual arrangement included; an online purchase alone does not establish whether clinical interpretation or confirmation occurred.

Consumer tests may cover only selected variants. A reported increased risk does not make disease inevitable, and a reduced-risk or unflagged result does not exclude every relevant condition. Discuss ongoing symptoms or family concerns with your clinician.

Do not change medicines, screening, procedures, diet or supplements from this page or a raw-data interpretation.

Ask whether a clinical result supports the claim, what remains uncertain and who can explain it.

Keep questions separate from original documents and use the receiving service's approved private route. Do not upload DNA files to SameCase or a public site.

For an existing clinical germline report labelled ‘variant of uncertain significance,’ use the separate VUS guide.